OCTON HEALTH 360
Holistic clinical AI
 All cancers
Use with patients
Cancer module

Brain & CNS Tumors

Multi-sequence MRI surveillance with O-(6)-MGMT / IDH molecular profiling.

Reporting system
WHO CNS5 (2021) molecular grading
Imaging modalities
  • MRI brain (T1 / T1c / T2 / FLAIR / DWI)
  • MR Spectroscopy
  • PET (FDG / amino-acid)
  • Pathology
Key findings OCTON surfaces
  • Ring-enhancing lesion with central necrosis
  • Mass effect / midline shift
  • Restricted diffusion (high-grade)
  • MR-spectroscopy ↑Cho/NAA
  • Leptomeningeal enhancement
Evidence base
  • NCCN CNS Cancers v2.2025
  • EANO Glioma Guidelines 2021
  • WHO Classification of CNS Tumours 5th edition
Risk questionnaire
  • · What is your age?
  • · Known NF1 / NF2 / Li-Fraumeni / Turcot syndrome?
  • · Prior cranial / craniospinal radiation?
  • · First-degree relative with primary brain tumor?
  • · New persistent headache, seizure, or focal neuro deficit?
  • · New cognitive / personality change?
See OCTON in action · early-detection demos
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Brain · CNS TumorYou're herehigh · 79/100MRI · WHO CNS5 Grade 3 · IDH-mut
IDH-mutant glioma WHO CNS5 grade 3 with imminent progression
T2 / FLAIR-hyperintense, mildly enhancing left frontal mass with mass effect — IDH-mutant astrocytoma WHO CNS5 grade 3.
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