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OCTON HEALTH
360
Holistic clinical AI
All cancers
Use with patients
Cancer module
Other / Unspecified
Holistic AI screen — apply when the suspected primary site is unknown or rare.
Reporting system
General radiologic descriptor + organ-specific guideline triage
Imaging modalities
CT
MRI
Ultrasound
X-Ray
PET-CT
Pathology
Key findings OCTON surfaces
Mass / lesion of indeterminate origin
Lymphadenopathy in a single basin
Abnormal contrast enhancement / restricted diffusion
Para-neoplastic syndrome with no obvious primary
Elevated tumor markers (CEA, CA 19-9, AFP, β-hCG, LDH)
Evidence base
Triage per the most relevant organ-system guideline
NCCN Occult Primary v1.2025 for cancer-of-unknown-primary work-up
ESMO CUP Clinical Practice Guidelines 2023
Risk questionnaire
· What is your age?
· Sex assigned at birth
· First-degree relative with any cancer under age 60?
· Known hereditary cancer syndrome (BRCA, Lynch, Li-Fraumeni, NF1, VHL, CDH1, MEN, Cowden, etc.)?
· Current or heavy past tobacco use?
· Heavy alcohol use (> 3 drinks/day)?
· BMI ≥ 30?
· HIV+, transplant, or chronic immunosuppression?
· Personal history of any prior cancer (second-primary risk)?
· Prior therapeutic radiation?
· Unexplained weight loss > 5% in 6 months?
· Persistent unexplained pain or fatigue > 4 weeks?
· Persistent lymph-node swelling > 4 weeks?
· Occupational carcinogen exposure (asbestos, benzene, arsenic, formaldehyde, etc.)?
See OCTON in action · early-detection demos
06 / 24
Thyroid · incidental
You're here
elevated · 50/100
US · ACR-TIRADS TR5
Sub-cm hypoechoic thyroid nodule with TIRADS 5 features
8 mm hypoechoic, taller-than-wide thyroid nodule with microcalcifications — TIRADS 5 (highly suspicious).
View demo
Ready to use this module?
Open OCTON and analyze a scan.
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