OCTON HEALTH 360
Holistic clinical AI
 All cancers
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Cancer module

Ovarian Cancer

BRCA-driven TVUS + CA-125 surveillance with O-RADS adnexal classification.

Reporting system
O-RADS US (1–5) / FIGO
Imaging modalities
  • Transvaginal Ultrasound
  • Pelvic MRI
  • CA-125 + HE4 (ROMA)
  • Pathology
Key findings OCTON surfaces
  • Solid components in adnexal mass (O-RADS US 4–5)
  • Ascites / peritoneal nodularity
  • Bilateral involvement
  • Rising CA-125 with HE4 elevation
  • Omental caking on cross-section imaging
Evidence base
  • NCCN Genetic / Familial High-Risk: Ovarian v1.2025
  • USPSTF 2018 (Grade D): no general-population screening; surveillance for BRCA carriers
  • ESMO Ovarian Cancer Clinical Practice Guidelines 2023
Risk questionnaire
  • · What is your age?
  • · BRCA1 / BRCA2 / RAD51C / D / BRIP1 carrier?
  • · First-degree relative with ovarian / breast cancer?
  • · Lynch / HNPCC syndrome?
  • · Long-standing endometriosis?
  • · No full-term pregnancies?
  • · Menarche before age 12 / late menopause > 55?
See OCTON in action · early-detection demos
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Ovarian cancerYou're herehigh · 81/100TVUS · O-RADS US 4
O-RADS US 4 adnexal mass · BRCA1 surveillance catch
Right adnexal complex cystic-solid mass · 4.3 cm · solid component with arterial flow — O-RADS US 4 (intermediate-high risk).
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