Cancer module

Cervical Cancer

HPV-DNA + cytology co-testing with colposcopy / LEEP escalation.

Reporting system
Bethesda + FIGO 2018 staging
Imaging modalities
  • HPV DNA test
  • Cytology (Pap)
  • Colposcopy
  • MRI pelvis
  • Pathology
Key findings OCTON surfaces
  • High-grade squamous intraepithelial lesion (HSIL)
  • HPV 16 / 18 persistent positivity
  • Acetowhite epithelium with abnormal vasculature
  • Parametrial / vaginal extension on MRI
  • Pelvic lymphadenopathy
Evidence base
  • USPSTF 2018 (Grade A): co-testing every 5 yr, age 30–65
  • ACS 2020 — primary HPV testing every 5 yr from age 25
  • WHO Cervical Cancer Elimination Initiative 2030
Risk questionnaire
  • · What is your age?
  • · Persistent high-risk HPV (16/18) positivity?
  • · Current smoker?
  • · HIV-positive or chronic immunosuppression?
  • · In-utero diethylstilbestrol (DES) exposure?
  • · Completed HPV vaccination series?
  • · No Pap / HPV co-test in > 5 years?
See OCTON in action · early-detection demos
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Cervical cancerYou're herehigh · 71/100Colposcopy · Bethesda HSIL
HSIL caught from persistent HPV-16 + colposcopy
High-grade squamous intraepithelial lesion (HSIL · CIN 2-3) on directed colposcopy biopsy — pre-invasive disease curable with LEEP.
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