Cancer module

Colorectal Cancer

Polyp, mass and wall-thickening detection on colonoscopy, CT colonography & pathology.

Reporting system
Paris classification / AJCC T-stage
Imaging modalities
  • Optical Colonoscopy
  • CT Colonography
  • FIT / Stool DNA
  • Histopathology
Key findings OCTON surfaces
  • Sessile / pedunculated polyp > 10 mm
  • Asymmetric bowel-wall thickening
  • Apple-core stricture
  • Pericolic fat stranding / adenopathy
  • Synchronous lesions
Evidence base
  • USPSTF 2021 (Grade A/B): start screening at age 45
  • ACS 2024 Colorectal Cancer Screening Guideline
  • BMJ 2022;376:e068714 — early-onset CRC under 50
Risk questionnaire
  • · What is your age?
  • · First-degree relative with CRC or advanced adenoma?
  • · Known Lynch syndrome or FAP?
  • · Ulcerative colitis or Crohn's colitis > 8 years?
  • · Prior adenomatous or serrated polyps?
  • · Current or former smoker?
  • · High red / processed meat, low-fiber diet?
  • · BMI ≥ 30?
  • · Physically inactive (< 150 min/week exercise)?
See OCTON in action · early-detection demos
04 / 24
Colorectal cancerYou're hereelevated · 55/100ENDOSCOPY · Paris Is + IIa
8 mm tubulovillous adenoma found at first screening colonoscopy
8 mm tubulovillous adenoma in the sigmoid colon — pre-malignant polyp removed cleanly.
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