OCTON 360
Sign up
Early-detection demo · Colorectal cancer

8 mm tubulovillous adenoma found at first screening colonoscopy

8 mm tubulovillous adenoma in the sigmoid colon — pre-malignant polyp removed cleanly.

Patient: Daniel · 50 · first-degree FDR with colon cancer at 55Modality: ENDOSCOPYRisk: elevated · 55/100
Share
01

Risk profile

What OCTON knew before the scan
Risk
55
elevated
Tier
elevated
Average-build, no GI symptoms. Father diagnosed with sigmoid adenocarcinoma at 55. No prior screening (USPSTF says start at 45 for average risk; 40 if FDR was <60).
Contributing factors
  • First-degree relative with CRC <60+24
  • Age 50 (no prior screening)+18
  • Western diet, low fiber+8
  • Sedentary lifestyle+5
Narrative

Daniel has elevated familial risk — his father's diagnosis under 60 places him in the 'high-risk family' bucket. NCCN recommends starting colonoscopy at age 40 or 10 years before the relative's age at diagnosis (whichever is earlier). He's 5 years overdue.

02

Scan + AI report

What ENDOSCOPY found · White-light + NBI colonoscopy, sigmoid colon at 30 cm
ENDOSCOPY · DEMO
Paris Is + IIa
OCTON · scanning · live
conf 0.82
OCTON Impression · 82% confidence

8 mm sessile polyp at 30 cm in the sigmoid colon. Surface pit pattern (Kudo IIIL/IV on NBI) and JNET 2A appearance suggest tubulovillous adenoma without high-grade features. Snared en-bloc.

Findings
  • 8 mm sessile polyp, sigmoid colon (30 cm from anal verge) · Sigmoid colon8 mm
  • JNET type 2A (low-grade adenoma surface pattern) · Polyp surface
  • No depression, no spontaneous bleeding, no ulceration · Polyp
  • Cecum reached, prep adequate (BBPS 8) · Right colon
Differential diagnosis
  • Tubulovillous adenoma, low-grade dysplasia72%
  • Tubular adenoma, low-grade dysplasia18%
  • Sessile serrated lesion7%
  • Hyperplastic polyp3%
Recommended actions
  • ▸Endoscopic mucosal resection (EMR) — completed during this procedure
  • ▸Histopathology to confirm dysplasia grade and margins
  • ▸Surveillance colonoscopy in 3 years per US Multi-Society Polypectomy Guidelines
Caveats
  • AI surface-pattern classification has ~85% accuracy versus expert endoscopist.
  • Histology is the gold standard; resect-and-discard policy is institution-dependent.
03

360° Preventative plan

Drugs · surveillance · diet · exercise · lifestyle — generated for this case
Clinical anchors
Drugs · labs · imaging · surveillance
Medical
FIT (annual interval option for low-risk years)
FrequencyAnnual
Startsage 45
USPSTF 2021 Grade A
Monitoring
Screening colonoscopy
FrequencyEvery 5 years (high-risk family) · 3 years post-polypectomy
Startsage 40
NCCN Colorectal Screening v1.2024 · USMSTF post-polypectomy guidelines
Lifestyle 360°
Diet · exercise · sleep · stress — the behaviours that move the needle
Diet
Lifestyle: 25–30 g fiber/day, ≥150 min/wk activity, limit red/processed meat
FrequencyOngoing
Startsage 18
WCRF/AICR 2018
04

What changed

The early-detection win

Daniel was overdue. The AI surfaced a sessile polyp the human eye nearly missed during a fast withdrawal — automatically pausing the video frame and outlining the lesion. EMR-removed in the same session; histology confirmed tubulovillous adenoma with low-grade dysplasia. Survival benefit of polypectomy: 53% reduction in CRC mortality (NPS, NEJM 1993). Surveillance is now scheduled at 3 years.

Run this for yourself

Open the colorectal cancer module on your own data.

Take the risk questionnaire, upload your scans, and have OCTON build your own preventative plan — same pipeline, your data.

Cancer module →Get started