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Endometriosis Pain + Nutrition

Endometriosis affects ~10% of women. Anti-inflammatory diet + pelvic-floor physio + (in many) hormonal suppression reduces pain by 40-70% in RCTs; multimodal care is first-line.

Nutrition
Pattern

Anti-inflammatory Mediterranean + reduced red meat

Foods to emphasise
  • Fatty fish 2-3×/wk (omega-3 anti-inflammatory)
  • Leafy greens
  • Berries
  • Cruciferous vegetables (oestrogen metabolism)
  • Turmeric, ginger
  • Flaxseed (lignans)
Foods to limit
  • Red + processed meat (associated with risk)
  • Trans fats
  • Excess alcohol
  • Refined sugar
Exercise
Aerobic

Moderate; can flare with high-impact during flares.

Strength

2-3×/wk modulated to symptoms.

Flexibility

Daily yoga; pelvic-floor down-training in conjunction with physio.

Weekly target

150 minutes

Supplements
Omega-3
2-3 g/day
RCT
Anti-inflammatory + pain reduction.
Magnesium glycinate
300-400 mg/day
observational
Cramping.
Vitamin D3
1000-2000 IU/day
observational
Low D associated with severity.
Curcumin
500-1000 mg/day with piperine
observational
NAC
600 mg × 3/day
RCT (small)
May reduce endometrioma size.
Monitor + cadence
What to track
  • Pain diary + cycle tracking
  • Functional impact
  • Symptom escalation triggers
  • Mental health screening (depression + anxiety common)
Red flags — seek care
  • Acute severe pelvic pain with fever → rule out PID, torsion, abscess — ER
  • Bowel obstruction signs (bilious vomiting, no flatus) → ER
  • Suicidal ideation from chronic pain → urgent psych
Sources
  • ESHRE Endometriosis Guideline 2022
  • ACOG Practice Bulletin 114 (2018)
  • NICE NG73 Endometriosis 2017
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